The transfer RNA of certain Enterobacteriacae contain 2-methylthiozeatin riboside (ms2io6A) an isopentenyl adenosine derivative
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چکیده
منابع مشابه
Presence of the hypermodified nucleotide N6-(delta 2-isopentenyl)-2-methylthioadenosine prevents codon misreading by Escherichia coli phenylalanyl-transfer RNA.
The overall structure of transfer RNA is optimized for its various functions by a series of unique post-transcriptional nucleotide modifications. Since many of these modifications are conserved from prokaryotes through higher eukaryotes, it has been proposed that most modified nucleotides serve to optimize the ability of the tRNA to accurately interact with other components of the protein synth...
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15 صفحه اولEnzymatic phosphorylation of adenosine and 2,6-diaminopurine riboside.
Knowledge concerning the nature of the biologic synthesis of purine or pyrimidine mononucleotides is relatively limited. A significant contribution was the demonstration by Ostern and coworkers (3) of the phosphorylation of adenosine to adenosine-5’-phosphate (A-5’-P) and adenosinetriphosphate (ATP) by means of crude yeast extracts. The energy source for this reaction was supplied by the fermen...
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By using [8-(14)C]-N(6)-(Delta(2)-isopentenyl)adenosine as a substrate, we detected the presence of enzyme activity in a crude extract of tobacco tissue that converts this cytokinin into adenosine. The extract also contains strong hydrolase activity that converts adenosine to adenine.
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1982
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/10.18.5663